Low back and leg pain is a common symptom among middle-aged and elderly people, most of them belong to general orthopedic diseases such as herniated discs and lumbar muscle strain. With the increasing incidence of tumors, there are also many patients with low back and leg pain who are finally diagnosed with spinal metastases. This disease, if not treated in time, can lead to paralysis, which can seriously affect the quality of life of patients and even endanger their lives. Main manifestations of spinal metastases 1. Pain is the most common complaint among patients with symptomatic spinal metastases, which can occur in 83-95% of patients and occurs weeks or months earlier than other neurological symptoms. The earliest symptom is thoracic or low back pain in the plane of lesion, which is generally mild and intermittent, and often does not attract attention and becomes persistent and severe with symptomatic treatment. Another most common symptom of spinal metastatic cancer patients is motor dysfunction. 60-85% of patients with metastatic spinal epidural compression have muscle weakness in one or more muscle groups. This muscle weakness may be related to myelopathy, radiculopathy, and can be caused by direct compression of neural structures by the tumor, or pathological fractures resulting in protrusion of fracture fragments into the spinal canal or nerve root canal. Breast, lung and prostate cancers as well as gastrointestinal tumors are more prone to bone metastases. The diagnosis of this disease is simple. For recurrent back and leg pain, it is best to perform CT or MRI of the spine and not just take painkillers. Treatment of spinal metastases Surgical treatment. The purpose of surgery for spinal metastases is to rebuild the stability of the spine, restore mobility and prevent the occurrence of spinal cord compression paralysis, as well as to relieve pain, improve the quality of survival and even prolong life. Radiation therapy. Radiotherapy can directly kill cancer cells in the bone and relieve cancer pain. Lymphoma and myeloma are sensitive to radiotherapy, breast cancer and prostate cancer metastasis are moderately sensitive to radiotherapy, sarcoma, kidney cancer and gastrointestinal tumor metastasis are not very sensitive to radiotherapy. Drug treatment. First, the location of the primary tumor is found, and chemotherapy, endocrine or targeted drug therapy can be selected according to the histological type of the primary tumor, chemotherapy sensitivity, receptor specificity, and gene mutation. If the spinal cord is highly compressed, hormones can be used routinely to reduce spinal edema and protect neurological function; for diffuse spinal pain that is not treated with bisphosphonates and primary tumors, palliative pain management can be performed according to the World Health Organization’s “three-step pain relief principle”.