Patients who experience headaches upon standing up and no pain in the flat position should have their blood pressure measured, paying special attention to posture-related hypotension. High blood pressure can trigger headache symptoms, but insufficient cerebral blood flow perfusion in hypotension can also trigger headache and dizziness, and even more pronounced discomfort. The relationship between blood pressure and posture is very close. When standing in a standing position, the effect of gravity will cause a relative decrease in blood pressure and inadequate cerebral blood perfusion, resulting in headache and dizziness. Patients can clarify whether this is related to standing hypotension by testing in the standing position and measuring blood pressure in the sitting, lying, and standing positions, respectively. If the relationship is not significant, other causes of the headache need to be looked for. Headache symptoms are common and there are many causes of headaches. In addition to being related to blood pressure, headaches caused by intracranial lesions, as well as otogenic and cervicogenic diseases, need to be identified. Patients should visit a regular hospital for differential diagnosis through ancillary tests.