In medicine, alcohol intoxication, commonly known as drunkenness, is an abnormal state of body functions that occurs after a patient drinks a large amount of alcohol (ethanol) at one time, and causes the most serious damage to the nervous system and liver. In medicine, it is divided into two types: acute intoxication and chronic intoxication, the former of which can bring greater harm to the patient in a short period of time and can even lead to death directly or indirectly. The latter brings cumulative harm to patients, such as alcohol dependence, mental disorders, alcoholic cirrhosis of the liver and induction of certain cancers (oral cancer, tongue cancer, esophageal cancer, liver cancer). About 20% of the alcohol consumed is absorbed in the stomach and 80% in the duodenum and small intestine. The amount of alcohol poisoning and lethality varies from person to person, with the amount of poisoning generally ranging from 70 to 80 grams and the amount of lethality ranging from 250 to 500 grams. Whether or not intoxication occurs is related to the following factors: the presence of food in the stomach (fast absorption in fasting), whether or not fatty food is consumed (fatty food can slow down the absorption of alcohol), good or bad gastrointestinal function (absorption is rapid in those with good gastrointestinal function), and the ability of the human body to process alcohol as a conversion agent (those who can rapidly convert ethanol into acetic acid are less likely to be intoxicated). Clinical manifestations: 1. Simple intoxication Also known as ordinary intoxication, it is an acute poisoning caused by a large amount of alcohol consumption at one time. The severity of intoxication is related to the patient’s rate of drinking, the amount of alcohol consumed, the blood alcohol concentration, and individual tolerance. It is usually clinically divided into the euphoric, ataxic and somnolent phases. Mildly affected patients experience mental abnormalities after drinking, such as talkative and irritable, flushed or pale face, eye congestion, rapid heart rate, dizziness, and headache. As the disease progresses, patients develop unstable gait, clumsy movements, slurred speech, incoherent speech, blurred vision and double vision, and may have nausea and vomiting. Patients with severe poisoning are in a comatose state, with pale face, blue lips, wet and cold skin, decreased body temperature, shallow breathing and dilated pupils. Severe cases fall into deep coma, blood pressure drops, breathing is slow, heart rate accelerates until death by exhaustion. 2.Complex intoxication Refers to the sudden appearance of strong psychomotor excitement and severe confusion during or after drinking a large amount of alcohol. At this time, the patient is more impaired in consciousness, and the psychomotor excitement is more intense and lasts longer. As a result, the patient is prone to violent behavior such as revenge injury, murder and destruction of property, and sexual crimes. Patients have only a vague awareness of their surroundings and partially or completely forget the seizure after the seizure, commonly known as “broken pieces”.