If the parents have syphilis, it is important to determine whether the child has syphilis and whether the parents have current syphilis or previous syphilis. If the parents have had syphilis in the past and have received regular treatment, and are not currently infectious, the child will not be born with syphilis. If the parents, especially the mother, are infected with syphilis during pregnancy, there is a higher probability that the newborn will be infected with syphilis, so prenatal checkups need to detect syphilis, and the newborn must receive regular treatment in time to avoid congenital syphilis. If the mother is infected with syphilis, prompt treatment is generally recommended. Treatment is by receiving benzathine penicillin once a week for a total of three prophylactic treatments in the first trimester and in the second trimester of pregnancy. During pregnancy, monthly hematological tests for syphilis are recommended. Blood tests for syphilis are required for both the mother and the fetus after pregnancy to evaluate the newborn for syphilis infection.