Cold and hot, general weakness, and headache are most often symptoms of infection, which are triggered by bacterial infections, viral infections, and mixed infections. When the body is invaded by bacteria, the central thermal neuron modulation point in the hypothalamus of body temperature is activated, which will increase the body temperature. In the case of viral infection, the thermal neurons are lowered, causing the body temperature to drop, and chills and chills can occur, followed by an increase in body temperature, alternately rising and falling, in a repeated process. This proves that the anti-inflammatory factors in the body are activated at the same time during the infection process, that is, the autoimmune state is also activated, and headache, dizziness, and weakness around the body also occur. In this case, it is recommended to go to the hospital, have blood tests to identify the cause, apply antibacterial or antiviral drugs, keep warm and drink more water to avoid delaying the disease.