The patient’s headache on the second day of drunkenness can be relieved by the following ways: First, it is recommended that the patient drink more honey water and watermelon juice, because honey water contains fructose, which can accelerate the decomposition of alcohol in the body and help reduce the patient’s headache. Watermelon juice has a diuretic effect can also accelerate the metabolism of alcohol, which can relieve the headache. Secondly, hot towels can be used on the headache area to stimulate blood circulation and reduce the symptoms of headache. The third, it is recommended to give the patient medication to relieve, such as giving the patient oral painkillers such as painkillers, acetaminophen, indomethacin or taking Chinese medicines, such as Zhen Brain Ning, Zheng Tian Wan, Dan Zhen Headache Capsules, etc., which can relieve the symptoms of headache to a certain extent.