The survival of patients with acute liver failure is closely related to its etiology, the promptness of treatment and the presence of other complications. Most patients have a short survival time of no more than one month, but some patients turn to chronic liver failure or achieve clinical cure after standardized treatment. There are many causes of acute liver failure, the main cause being the hepatitis virus, followed by the application of drugs (such as antipyretics and antituberculosis drugs), etc. The development of hepatitis virus may lead to cirrhosis at a later stage, and in severe cases, complications such as hepatic encephalopathy, ascites, and renal failure may occur. From the current clinical data statistics, if no active and effective treatment is taken, the morbidity and mortality rate is up to more than 70% with a survival time of no more than one month with purely medical intervention. Therefore, once the diagnosis of acute liver failure is clear, immediate medical attention should be sought to determine the progress of the disease and, if necessary, in situ liver transplantation to reduce the morbidity and mortality rate. In addition, patients with acute liver failure should strengthen oral and skin care, reduce physical exertion, eat a high calorie, low protein, easy to digest, high vitamin soft food, and maintain a good state of mind, which can also play a role in prolonging survival.