Headache is a common clinical symptom, and most patients who suffer from headache with nausea and vomiting will naturally go to an internist for treatment. Acute angle-closure glaucoma is a common cause of headache. Acute angle-closure glaucoma is a common and frequent clinical disease, usually seen in elderly people over 50 years old, with sequential or simultaneous onset in both eyes. At the initial onset, there is only occasional mild headache, eye swelling or accompanied by vision loss, often triggered by emotional excitement, mental trauma, overexertion and other factors. In acute attacks, patients can have severe headache and eye pain in a very short period of time, the eye is harder during pain, vision decreases sharply, and in severe cases, only the immediate index can be distinguished or there is only light perception, which can be accompanied by nausea, vomiting, chills, fever, etc. A few people can also have diarrhea symptoms, and inexperienced The inexperienced internist may sometimes misdiagnose it as acute gastroenteritis or intracranial hypertension. In acute angle-closure glaucoma, the intraocular pressure increases sharply in a short period of time, exceeding the normal limit and causing the eye to harden. The increased intraocular pressure can cause headache, eye pain and a series of systemic symptoms mentioned above. Persistent increased intraocular pressure can cause irreversible damage to the optic nerve in the fundus of the eye. Because the optic nerve tolerates high intraocular pressure very poorly, damage can occur in as little as 16 hours, so an acute attack of closed-angle glaucoma is an ophthalmic emergency and immediate measures must be taken to lower the intraocular pressure to a normal range. When the headache, ocular and systemic symptoms are relieved or disappear, surgical treatment should be considered. Once the opportunity to save the eye is missed, it can cause permanent damage to vision and in severe cases, complete blindness. Therefore, patients who have headache and eye pain with vision loss should go to the ophthalmology department immediately to avoid delaying the disease and causing irreversible consequences. Links to related knowledge: Common clinical manifestations of acute angle-closure glaucoma: 1. Headache: Headache is often the first symptom of glaucoma patients. But unlike the general headache can be relieved by sedative and painkilling drugs. Because glaucomatous headache is produced by the elevated pressure of the eye, it can be reduced or eliminated only after the pressure of the eye is reduced. Glaucoma headache is often accompanied by orbital and nasal root distension, and the headache in one eye may also manifest as a severe migraine. 2. Nausea and vomiting: Glaucoma attacks are mostly accompanied by severe nausea and vomiting, which are generally ineffective with antiemetic drugs and can be reduced or eliminated only when the IOP drops. Nausea and vomiting caused by gastrointestinal diseases are also very common, but they are also often accompanied by abdominal pain or changes in the number of stools and other symptoms, which can be mostly relieved with anti-vomiting and analgesic drugs, which can be distinguished. 3, rainbow vision: refers to the onset of the patient, look at the light will have a rainbow-like circle of light around the light. The outer circle is red and the inner circle is green or violet-blue. This is due to an increase in intraocular pressure, which causes corneal edema due to impaired fluid circulation in the eye and produces refractive changes. When the intraocular pressure returns to normal, the iris disappears. 4, vision loss: glaucoma disease in acute attacks have obvious vision loss, in addition to corneal edema, the main reason is the increased intraocular pressure caused by damage to the optic nerve. The higher the intraocular pressure, the greater the pressure on the optic nerve, and the more pronounced the loss of vision.