The liver is the largest digestive gland in the body, responsible for the metabolism and detoxification of nutrients, and has an important endocrine role, known as the “chemical factory” of the human body. The most common liver lesion in China is viral hepatitis B, followed by alcoholic hepatitis, fatty liver and cirrhosis of the liver related to alcohol consumption. During the holidays, the reunion of friends and family will bring us spiritual pleasure, but excessive excitement, fatigue, alcoholism, improper diet, etc. may induce liver disease, especially for patients with chronic liver disease, cirrhosis will make the condition worse, so patients with liver disease during the holidays should pay special attention to protect their liver. 1, avoid overeating For general liver disease patients, we advocate a high protein, high vitamin, low fat diet, but do not be in the holiday season, a moment of pleasure, overeating. Excessive intake of protein, not only can not be fully utilized, but also may increase the burden on the liver, and for patients who already have obvious liver function abnormalities may even produce a fatal threat. These patients with liver disease have digestive problems, and the excess protein in the intestine that cannot be absorbed will be formed by bacterial enzymes and absorbed into the blood, causing a sharp increase in blood ammonia and leading to liver coma. A large amount of fat intake will also increase the burden on the liver and accelerate the fatty degeneration of liver cells, resulting in fatty liver. Therefore, patients with active hepatitis should adhere to a light diet, mainly carbohydrates, and eat more fresh vegetables and fruits. In addition, patients with cirrhosis should also avoid eating rough, spicy, raw and fried foods to prevent the varices of the esophagogastric fundus vein from being cut, resulting in upper gastrointestinal bleeding. 2, strictly avoid alcohol alcohol is a long-standing enemy of the liver, its chemical composition is ethanol, mainly through the liver metabolism, in the role of oxidase, into acetaldehyde and acetic acid. Ethanol and acetaldehyde are both highly reactive oxidants, especially acetaldehyde has a stronger toxic effect on liver cells. Both chemicals can cause excessive oxidation of liver cell membranes, disrupt liver cell repair, interfere with liver metabolism of proteins and sugars, and can lead to the accumulation of fat in liver cells and the formation of a fatty liver. Some people experience flushing after drinking alcohol, which is due to the lack of acetaldehyde oxidase in the body and the accumulation of acetaldehyde in the body, causing capillary dilation. When people with liver disease drink alcohol, the amount of acetaldehyde in their bodies is several times higher than that of normal people, making it easier to cause liver damage. The higher the degree of alcohol and the greater the intake, the more serious the damage to the liver. The more you drink, the more serious the damage to your liver will be. Drinking alcohol for people with liver disease will only aggravate the disease and accelerate the process of liver fibrosis and cirrhosis. During the holidays, friends and relatives get together and raise a glass of wine to celebrate this is common sense, as the saying goes: no wine is not a good seat. However, as a patient with liver disease, you should be sensible, put your health first, and strictly avoid alcohol, including liquor, beer and fruit wine. In the case of a feast, you can use tea instead of wine, juice instead of wine, raise your golden bottle and toast each other back with your sincerity. 3, pay attention to rest Liver disease patients during the holiday period for the activities they participate in must be measured, try not to break the original life pattern. No matter what activities you participate in, make sure you get enough sleep and do not overwork yourself. The disruption of biological clock, mental fatigue and physical overexertion can cause the body’s resistance to decline and affect the function of the liver. Studies have shown that the blood flow to the liver is reduced by 40% in the upright position compared to the recumbent position, and the blood flow to the liver is reduced by 80% to 85% during exercise compared to the recumbent position. For a healthy person, this would not have much effect on the liver. However, for patients with liver disease, liver cells are very sensitive to ischemia and hypoxia, and a slight decrease in liver blood flow may lead to hepatocyte degeneration and necrosis and abnormal liver function. Therefore, patients whose liver function has been relatively stable can participate in some recreational and sports activities in moderation, with the amount of activity not feeling fatigue, but for patients with obvious abnormal liver function, emphasis should be placed on “rest and recuperation”, or even bed rest. In addition, it should be especially emphasized that patients with cirrhosis and esophageal varices should avoid participating in sports such as weight lifting, high jumping and long jumping which can increase abdominal pressure to prevent rupture and bleeding of the varices of esophagogastric fundus. 4, health food and other good health food can provide the necessary amino acids, trace elements and vitamins, which are beneficial to human health, but some health food contains preservatives and artificial colors that are toxic to the liver, in addition to the nutrients indicated. Therefore, patients with liver disease should be selective when consuming health food, and it is best not to consume health food containing preservatives and artificial colors. Young couples who are reunited for a long time during the holidays, if the woman has liver disease and needs contraception, they should choose a contraceptive tool, of which condoms are the best, so as to avoid contact between the male and female genital secretions and infection with hepatitis virus, but also to avoid the damage to the liver caused by taking contraceptive pills. Most contraceptives are hepatotoxic, especially estrogens (such as megestrol, norethindrone or ethinyl estradiol), which can sometimes cause serious liver damage even after a single dose. Women who love beauty should be aware of allergic reactions from cosmetics and hair dyes, as well as the possible effects on liver function. Do not abuse diet pills. The chemical components in some diet pills (such as fenfluramine) have a strong toxic effect on the liver, and patients with liver disease should be especially careful. There is no real diet pill in the world so far. May the glorious sunshine of the holidays leave us with a big smile!