How to confirm the diagnosis of glioma

If we suspect a possible intracranial lesion, combined with the patient’s symptoms and neurological signs, the most convenient and quick way is to check a cranial CT, which can be done in a level 1 or level 2 hospital, after the CT, we have a preliminary judgment of the intracranial situation, and if there is a problem considering the possibility of glioma, then we can further check magnetic resonance imaging (MRI), which has There are many sequences of MRI, such as scanning (T1, T2) and enhancement, diffusion-weighted imaging (DWI), magnetic resonance spectral imaging (MRS), diffusion tensor imaging (DTI), magnetic susceptibility weighted imaging (SWI), perfusion imaging (PWI), etc. The most basic sequences for diagnosing glioma MRI are scanning, enhancement, diffusion-weighted imaging (DWI) and wave (MRS) examination. Most gliomas can be diagnosed with these basic sequences. If it is still difficult to make a definitive diagnosis, then proceed to perfusion imaging (PWI). Perfusion is very valuable in identifying tumors, encephalitis, and infarcts. In addition positron emission computed tomography (PET) is also meaningful for the diagnosis of glioma. PET imaging is done by radionuclide labeling of substances necessary for life metabolism, such as glucose and methionine, and it responds to the metabolic activity of the tumor, and if it is hypermetabolic, then the possibility of tumor is high. After these three tests, we will have a basic judgment of intracranial tumor, including location, size and nature, whether it is a tumor, which kind of tumor, benign or malignant. It should be noted that no matter how much the imaging examination looks like tumor, tumor pathology diagnosis is the final diagnosis of tumor.