Depression is a type of mental illness that is very common in society nowadays. Depression is very related to gastrointestinal symptoms, and some patients with depression for a longer period of time will cause various symptoms in the digestive tract, the most common digestive symptoms are upper abdominal discomfort, such as frequent nausea, loss of appetite, abdominal pain, and the pain symptoms in the abdomen are not obvious. The most common digestive symptoms are upper abdominal discomfort, such as frequent nausea, loss of appetite, abdominal pain, and painful abdominal symptoms are not obvious. Patients mainly show vague abdominal pain and discomfort, while gastroscopy does not reveal any special abnormalities, and some patients have unexplained diarrhea and unformed stools.