Syphilis hand symptoms are mainly manifested as palmoplantar syphilis rash, palmoplantar syphilis rash is polymorphic, its form can be diverse, the distribution can be scattered or dense. But most of the syphilis rash has the following characteristics: First, most of the syphilis rash color is dark red or bright red, pressure does not fade, the color is relatively intense, not bright, not light, like the symptoms of “allergic purpura” rash, the color is darker. The distribution of the syphilis rash in most people is mainly in the palmoplantar area, that is, the middle part of the palm of the hand. Most people start with a single syphilis rash and gradually form a multiple syphilis rash. The majority of people have no special symptoms, many patients may not be painful or itchy on a few bumps, it is easy to be ignored, as the syphilis rash will gradually fade. The actual effect of the treatment is that the syphilis rash can quickly fade away without leaving a trace after the regular syphilis repellent treatment.