White dots at the corners of the mouth, for children, may be caused by inflammation of the oral mucosa, may also be a manifestation of vitiligo; for adults, it is necessary to consider factors such as sebaceous gland ectopia, cornea, etc., need to deal with the causative factors: a. Children 1, thrush: caused by Candida infection, resulting in inflammation of the oral mucosa, manifested as white dots on the surface of the mucosa in the mouth, occasionally appear in The mucous membrane at the corners of the mouth, accompanied by dry mouth and other discomfort. It is necessary to apply antifungal drugs for anti-infection treatment, at the same time can be used sodium bicarbonate solution gargle, in order to inhibit the growth and reproduction of Candida; 2, vitiligo: caused by melanocyte destruction of the corner of the mouth skin white spots, may be related to the autoimmune system disorders or genetic factors, mainly manifested as white patches of varying sizes, mostly without conscious symptoms. Corticosteroids can be applied, or local topical calcium phosphatase inhibitors to stop the spread of white spots to achieve the purpose of treatment. Second, adults 1, sebaceous gland ectopia: white spots at the corners of the mouth may be caused by physiological variation in the development of sebaceous glands and sebaceous gland hyperplasia, resulting in the appearance of sebaceous gland ectopia, manifested as white or yellowish papules on the skin at the corners of the mouth, generally without itching or pain. It is harmless to the human body and generally does not require treatment. If it affects the aesthetics, it can also be treated by way of liquid nitrogen freezing and laser; 2. milia: related to genetic factors or damaged sweat ducts, it can manifest as white or yellow-white hard papules at the corners of the mouth.