A variety of causes can lead to intractable headache, such as brain tumor, encephalitis, trauma, vascular spasm, vascular stenosis, blood circulation disorder, rhinitis, nerve compression, cervical spondylosis and so on. Therefore, when headache occurs, you should first think about what the cause is, and if it is not clear, you should go to hospital for examination, such as head CT, head MRI, cerebral angiography, cerebrovascular ultrasound, etc. There are two most common types of intractable headaches: vascular headache and neurological headache. Vascular headache is caused by the abnormality of the blood vessel structure in the head, which is characterized by irregular attacks of headache, mainly swelling pain, sometimes pulsating headache, accompanied by dizziness, nausea and even vomiting, which can last for hours or even days, and requires bed rest in severe cases. At present, cerebral angiography can clarify the blood vessels and sites of lesions, and on this basis, interventional therapy or minimally invasive surgical treatment can cure headache. Therefore, patients suspected of having vascular headache should go to regular hospitals for examination as soon as possible in order to cure headache completely and early. Neuropathic headache is a pain like pins and needles in a certain area of the head, which can be in the form of strips or pieces of pain in the head area, and the pain is mostly radioactive in character, and each attack lasts for a short period of time, but it can be recurrent and severe, mostly not accompanied by nausea and vomiting, and pain can be temporarily relieved by pain relief tablets and carbamazepine. This kind of pain is mostly caused by nerve compression, so it is most critical to identify the nerve and the area of compression, and the diagnosis can be confirmed with the help of doctor’s examination and imaging.