Transarterial chemoembolization (TACE) for hepatocellular carcinoma, commonly known as interventional therapy, is now commonly promoted as the main non-surgical therapy for the treatment of intermediate to advanced primary hepatocellular carcinoma. Its principle is to shrink the tumor by blocking the blood supply to the tumor, causing severe ischemia and necrosis, although some problems that may be encountered at the end of the treatment need to be noted, such as local bleeding and hematoma from the puncture, gastrointestinal reaction, fever, pain etc. 1.Puncture local bleeding and hematoma: After the treatment, patients should pay attention to the puncture site with pressure for 12 hours and absolute bed rest for 24 hours, and avoid bending and pressure on the puncture side of the limb to prevent the puncture port from loosening or moving, which may cause bleeding and edema at the puncture site, etc. Once the condition is found, the doctor should be informed immediately. 2, gastrointestinal reaction symptoms: the application of a large number of chemicals and contrast agents during interventional treatment can cause nausea and vomiting, and severe nausea and vomiting can cause spasmodic contraction and rupture of capillaries in the mucosa of the stomach and esophagus near the cardia and gastrointestinal bleeding, so antiemetic drugs should be applied after the operation, and to prevent and control patients from severe nausea and vomiting. 3.Fever: After interventional treatment, patients will have fever, which is caused by coagulative necrosis of tumor and absorption heat. 4. Pain: Pain is also a problem after interventional treatment. The pain is mostly caused by swelling of the embolization chemotherapy site and swelling of the right upper abdomen, which is generally not a big problem.