After nicotine poisoning, it is necessary to immediately stop exposure to nicotine and maintain ventilation, and those with more serious symptoms are recommended to go to the hospital immediately for oxygen inhalation, gastric lavage and other rescue treatments. Nicotine, also known as nicotine, is the main ingredient in tobacco and can be volatilized with the burning of tobacco. It is a colorless oily liquid, strongly alkaline and highly toxic. Inhalation, internal use and skin contact with nicotine can lead to nicotine poisoning. Mild poisoning can be manifested as dizziness, nausea, vomiting, etc., which need to be immediately removed from nicotine exposure, maintain ventilation, drink plenty of water, rest, and can be relieved after 1 to 2 hours. Severe patients may show urinary incontinence, respiratory muscle paralysis or even respiratory arrest, impaired consciousness, etc., must be immediately sent to the hospital for treatment, common treatment measures include oxygen inhalation, gastric lavage if swallowed by mistake, detection of electrolyte levels and vital signs, and replenishment of body fluids and electrolytes if the vomiting is severe. Nicotine poisoning is most common in the smoking population, smoking is harmful to health, it is recommended to quit smoking as soon as possible.