Depression can present with generalized weakness, where patients feel that their whole body has collapsed and fallen apart, often reporting that they are too tired, have no energy, and feel exhausted and exhausted even without doing anything. In addition to the above clinical manifestations, patients may also experience loss of libido or even complete loss of libido, menstrual disorders, amenorrhea, loss of appetite, weight loss, and other symptoms. Of course, some patients may experience symptoms related to autonomic dysfunction, such as dizziness, headache, panic, palpitations, hot and cold sensation and numbness of the skin, etc. Some patients may also show disorders of internal organ functions, such as abdominal distension, abdominal pain, frequent and urgent urination, etc. Patients often visit major departments of general hospitals for related tests because they are not feeling well, but the test results are difficult to explain the patient’s symptoms, or the tests are not positive at all, and they finally go to the psychosomatic medicine department of general hospitals to seek help from specialists.