Malignant pleural effusion, called “hanging drink” in Chinese medicine, is often caused by lung cancer, breast cancer, malignant lymphoma, liver cancer, ovarian cancer, mesothelioma and malignant tumors of unknown origin. The clinical symptoms of malignant pleural effusion often include cough, chest tightness, dyspnea and chest pain. At present, clinical reliance on thoracentesis and aspiration cannot solve the gathering of malignant pleural effusion, and the effect is very unsatisfactory. In particular, it makes the growth of malignant pleural effusion more rapid. Repeated thoracentesis is also prone to infected pleural effusion package and hypoproteinemia, the latter of which can aggravate the accumulation of pleural effusion. The purpose of treating malignant pleural effusion is to relieve the various clinical symptoms caused by pleural effusion and to prevent the reaccumulation of pleural effusion. It can be summarized as follows: 1.Etiological treatment: actively treat the primary disease. 2.Exclusion of effusion: a small amount of effusion can be left untreated to be absorbed naturally, while a medium amount of effusion with symptoms of compression should be extracted by thoracentesis, 2 to 3 times a week. The amount of fluid should not be too much and too fast to prevent pleural shock and ipsilateral dilated pulmonary edema. 3.Drug injection: Cancerous pleural effusion can be injected with anti-cancer drugs or tetracycline after thorough drainage to produce chemical stimulation causing adhesions to reduce the compression symptoms caused by the excessive growth of cancerous pleural fluid. 4.Pleural cavity intubation and drainage: If repeated aspiration of cancerous effusion is not effective, a thin catheter can be inserted to perform closed drainage, and then inject drugs after striving for complete drainage in about 72 hours. 5.Thoracoscopic pleural stripping intra-thoracic drug delivery: due to the features of small trauma and quick recovery, especially for malignant pleural effusion of unknown cause, after the diagnosis of thoracoscopic pathology is confirmed, part of the wall pleura is stripped and drug infusion is performed under direct vision to reduce the symptoms caused by excessive growth of cancerous pleural fluid. Malignant pleural effusion belongs to the category of “hanging drink” in traditional Chinese medicine, which is generally divided into three stages. Malignant pleural effusion is generally high in volume and prone to recurrence. Its occurrence is mostly caused by water-liquid metabolism disorder which leads to water-liquid not following normal channels and flowing in the chest. The pathogenesis belongs to the original deficiency and the mixed deficiency and actuality. The original deficiency lies in the increasing deficiency of qi, blood, yin and yang; the symptom lies in the increasing exuberance of cancer toxicity and the deteriorating contrast between the forces of good and evil. Using the integrated therapy of Chinese and Western medicine, herbal thoracic infusion plus herbal evidence-based treatment, the effusion basically disappeared in each patient, and the symptoms were relieved, and the treatment was still effective in some patients with recurrence of effusion. Under the premise of unknown etiology, pleural dissection after thoracoscopic pathological biopsy, assisted by intracavitary herbal infusion, has the characteristics of less toxic side effects, can improve symptoms, improve the quality of life, prolong survival, etc., especially for old and weak patients can be the first choice of treatment.