Are you bothered by gout?

  Gout has existed for as long as there have been humans on earth. Gout is a disorder of purine metabolism in the body, resulting in a surge of uric acid in the blood and the production of uric acid stones, which can damage the joints, organs and other tissues of the body and lead to “gouty arthritis”, “gouty kidney disease” and “gouty heart disease”. “Gouty heart disease” and other diseases.   The first hospital of Huzhou Normal College, Department of Urology Zhong Huan historical records, suffering from gout, such as Julius Caesar, Louis VII, Martin Luther, etc., so gout is also known as “imperial disease”. According to the analysis report of China Disease and Health Survey Center in 2004, due to the improvement of modern living standard, people consume too much purine-rich meat, alcohol and other foods, today’s gout is no longer the patent of the emperors. According to statistics, the number of patients with hyperuricemia in China has reached 120 million, including more than 75 million gout patients, and is rapidly increasing at an annual growth rate of 9.7%. Gout has become the second largest metabolic disease in China after diabetes, devouring people’s health indiscriminately.  ”The early diagnosis and treatment of gout is very important, not only to pay attention to treatment, and early prevention, the following list to overcome the gout of the 5 major decisions: 1, do not mistakenly believe in the prescriptions, because the drugs in these prescriptions, not after the selection and experimentation, not to mention the advanced technology to enhance, there is harm to the human body and side effects, resulting in the deterioration of gout.  2, maintain the ideal weight, avoid obesity. Obesity is more likely to become a high risk group for gout; if you can implement the principle of eating eight portions, you can reduce your weight and use the clear uric acid value to significantly reduce.  3, moderate the amount of alcohol. No matter what kind of alcoholic beverages, will lead to the rise of serum uric acid value, especially ice and beer, the two together, the gout patients to ensure that a touch immediately.  4 . Proper exercise. Often do swimming, slow walking, playing tai chi, etc., normal people, help the serum uric acid value down, but also to increase heart function. Gout patients are conducive to the recovery of the disease, but avoid long-term excessive and intense exercise.  5, gout patients, food ban and transport of. High protein substances and high purine food, namely animal offal, such as liver, kidney, pancreas, brain and gravy, meat extract, sardines, etc. should be completely prohibited. All spicy and irritating foods such as alcohol, coffee, chili and curry seasonings are also not recommended, and beans should be eaten sparingly.  ”The gout is a disease caused by the disorder of purine metabolism in the body, manifested as hyperuricemia, the precipitation of uric acid salts in the joints, kidneys and connective tissue. In acute attacks, urate microcrystals are deposited in the joints and cause local granulocyte infiltration and inflammation.  Allopurinol (allopurinol) is an isomer of hypoxanthine. Hypoxanthine and xanthine can be catalyzed by xanthine oxidase to produce uric acid. Allopurinol is also catalyzed by xanthine oxidase to convert to alloxanthine; both it and alloxanthine inhibit xanthine oxidase. Therefore, the production and excretion of uric acid are reduced by allopurinol, preventing the deposition of urate microcrystals and the development of chronic gouty arthritis or nephropathy. Allopurinol is associated with few adverse effects, with occasional skin rash, gastrointestinal reactions, elevated transaminases, and leukopenia.  Probenecid, also known as benemid, is completely absorbed orally, with a plasma protein binding rate of 85% to 95%; most of it is excreted through the active secretion of the renal proximal tubule, and is excreted slowly because of its large lipid solubility and easy reabsorption. This drug competitively inhibits the transport of organic acids by renal tubules, inhibits the reabsorption of uric acid by renal tubules, and increases uric acid excretion, which can be used to treat chronic gout. It is not suitable for acute gout because it has no analgesic and anti-inflammatory effects.  Benzbromarone is similar to propanosol in that it reduces the reabsorption of uric acid in the renal tubules and promotes its excretion. The daily dosage is 20-100mg, preferably starting from 20mg/day and gradually increasing. Adverse effects include headache, nausea and diarrhea.  Colchicine has a selective anti-inflammatory effect on acute gouty arthritis, and the redness, swelling, heat and pain in the joints subside within a few hours after the drug is used. It has no effect on blood uric acid concentration and uric acid excretion, and its effect is to inhibit granulocyte infiltration during acute attacks.  This drug has a high number of adverse reactions. Gastrointestinal reactions are common. Watery diarrhea and bloody stools, dehydration, and shock occur in cases of poisoning; it also has damaging effects on the kidney and bone marrow.  Formulation and use Acetylsalicylic acid (acetylsalicylic acid) Antipyretic and analgesic 0.3-0.6g/dose, 3 times/day, after meals. Anti-rheumatic: 3~5g/day, divided into 4 doses, gradually reduce the dosage after the symptoms are controlled.