Indomethacin suppositories are usually administered anally, and the drug is absorbed relatively quickly, usually starting to take effect within half an hour after administration, and the body temperature begins to gradually drop in about an hour. Indomethacin suppositories belong to the non-steroidal anti-inflammatory drugs, the main role is to relieve fever and relieve joint and muscle pain symptoms, can be used for rheumatoid arthritis pain relief and tumor, hematologic system diseases of antipyretic treatment. Indomethacin suppositories can cause a slight bowel movement after anal administration, which is caused by the stimulation of the anus by the suppository, and patients are advised to defecate after half an hour to maintain the effect of the drug. Although indomethacin suppositories have a rapid onset of action, it varies according to individual patient sensitivity and body composition.