How much do you know about the causes of precocious puberty?

  1, idiopathic precocious puberty, also known as somatic precocious puberty, is caused by the hypothalamus’ decreased sensitivity to the negative feedback of sex hormones, resulting in premature secretion of gonadotropin-releasing hormone, which is more common in females, accounting for more than 80% of girls’ CPP, while only about 40% of boys.  2.Precocious puberty secondary to abnormalities in the central nervous system, including: ① tumors or occupying lesions: hypothalamic malformations, cysts, granulomas, ② central nervous system infections, ③ acquired injuries: trauma, post-operative radiotherapy or chemotherapy, ④ developmental abnormalities: hydrocephalus, optic septal hypoplasia, etc.  3, other diseases primary hypothyroidism.  4.Gonadal tumors Ovarian granulosa-vesicular membrane cell tumor, luteinoma, testicular mesenchymal cell tumor, teratoma, etc.  5, adrenal gland diseases adrenal tumors, congenital adrenal cortical hyperplasia, etc.  6.Exogenous Such as estrogen-containing drugs, food, cosmetics, etc.  7.Simple premature breast development, simple premature pubic hair development, simple premature development.