About 4% of patients with chronic nephritis develop uremia, and the time to progression to uremia can be long or short. Most patients with chronic nephritis can have long-term stable kidney function through effective treatment. However, some patients will slowly progress to uremia even after effective treatment, so renal failure should be delayed as much as possible and enter the uremic phase as late as possible. Clinically, renal preservation therapy such as Bailing Capsules, Jin Shui Bao Capsules, Dipyridamole and Benadryl can be applied. At the same time, we must avoid aggravating factors of renal function deterioration, such as infection, fever, vomiting, diarrhea, blood loss, fluid loss, high or low blood pressure, high uric acid, blood sugar and lipids, etc. We must avoid nephrotoxic drugs such as non-steroidal anti-inflammatory drugs and aminoglycoside antibiotics in general.