Prevalent areas of gout

The most common site of gout is the first metatarsophalangeal joint of both feet, while other common sites include the ankle, knee and hand joints, as well as the dorsum and heel of the foot. The basis of gout is hyperuricemia, a sterile inflammatory disease caused by the deposition of uric acid crystals around the joints as a result of long-term uncontrolled high uric acid. The specific pathogenesis is not yet very clear, men are more common, women are mainly seen after menopause, so there may be a certain relationship with sex hormones. The acute phase of gout can be treated with colchicine or non-steroidal anti-inflammatory drugs, such as etoricoxib tablets, and long-term treatment with uric acid-lowering drugs is recommended during the stable phase.