Theoretically, every man has the potential to develop prostate cancer. The incidence of prostate cancer increases with age and is significantly higher than the incidence of other neoplasms. 1:10,000 <39 years 1:103 40-59 years 1:8 60-79 years Basically, the incidence of prostate cancer doubles every 10 years after age 40, and the probability of prostate cancer in men aged 50 years is 10% compared to 70% in men aged 80 years. Regardless, the incidence of prostate cancer does not increase in most older adults, and the reason for this is that so many patients who die from other causes of prostate cancer do not have a clear diagnosis of prostate cancer before they die. Prostate cancer is more common in black Americans, with an incidence of 66%. However, African blacks have one of the lowest incidence rates of prostate cancer in the world. Asian American men have a lower incidence rate than Caucasians, but a higher incidence rate than native Asians. The Japanese currently have the lowest incidence of prostate cancer, while Switzerland has the highest. Prostate cancer is related to sex hormones. Men who undergo early orchiectomy (depot) rarely develop prostate cancer. Men with higher levels of sex hormones have a higher chance of developing prostate cancer. Body size is not significantly associated with the risk of prostate cancer; however, prostate cancer patients who gain weight early in life have more rapid cancer progression. Smoking does not increase the risk of prostate cancer, but prostate cancer is more likely to progress in smokers compared to non-smokers. Exercise can help reduce the risk of prostate cancer. The relationship between vasectomy and prostate cancer has not been clearly established. Some studies have demonstrated that vasectomy increases the risk of prostate cancer, but mostly in well-differentiated, low-grade, low clinical stage prostate cancer. Some studies have confirmed that vasectomy does not increase the risk of prostate cancer. Vasectomy is the cutting, ligation, or cautery of the vas deferens separately to prevent recanalization. Vasectomy does not affect testosterone production or blood entry; its effect is simply to prevent sperm from leaving the testes. The prevailing view is that vasectomy does not increase your risk of prostate cancer.