1. Hepatitis B vaccine and Hepatitis B immunoglobulin should be injected in different parts of the body as soon as possible after the birth of the child, and Hepatitis B vaccine should be injected once when the child is full term and once again at the age of 6 months. Chen Longyan, Department of Hepatology, Qilu Hospital, Shandong University 2. Don’t breastfeed and don’t chew rice to feed your child. 3. Regarding the need to inject hepatitis B immunoglobulin in the second trimester of pregnancy: according to the available research data, injection of hepatitis B immunoglobulin in the third trimester of pregnancy does not significantly reduce the chance of fetal infection with hepatitis B virus. Therefore, it is not recommended to inject hepatitis B immunoglobulin in the second trimester.4. Whether to take antiviral drugs in the second trimester: Taking anti-hepatitis B drugs in the second trimester can reduce the chance of fetus being infected by hepatitis B virus, but the antiviral drugs themselves may have the possibility of causing adverse reactions such as teratogenicity to the fetus. Therefore, the use of antiviral drugs should only be considered when the hepatologist evaluates the condition and considers that the benefits of taking antiviral drugs outweigh the disadvantages, and the informed consent should be signed.