There are about 90 million people with chronic HBV infection in China, and more than 1/3 of these patients have emotional disorders. From the date of infection, the negative impact of chronic hepatitis B virus on patients’ psychology, life and society as a whole far exceeds the disease itself. According to research studies, chronic hepatitis B patients’ evaluation of their quality of survival as well as health satisfaction is significantly lower than that of normal people, by rating four areas of evaluation of quality of survival, such as physiological, psychological, social relations and environmental, etc. The duration of the patient’s illness, economic situation, fatigue, gastrointestinal symptoms, somatic symptoms and laboratory tests are the main factors affecting the quality of survival of chronic hepatitis B patients . Their mood disorders are mostly manifested clinically as anxiety, depression, fear, interpersonal sensitivity, hostility, and loneliness, etc. Currently, the treatment of mood disorders in patients with chronic hepatitis B is often neglected, and there is no specific treatment in Western medicine, especially for patients with normal test results. Chinese medicine treatment in this field has obvious advantages, Chinese medicine believes that “the liver is the master of drainage”, “qi depression does not relax, wood does not reach”, “worry about depression move the liver to cause disease …… The liver is the master of drainage. The liver is the main drainage, has the role of drainage of the whole body qi, blood, fluid, to ensure its smooth operation. Chronic hepatitis B patients are suffering from long-term pain, social discrimination and the cost of long-term treatment, so that they are in a long-term negative mood, the liver is not draining, the qi is not smooth, and over time, resulting in depression, liver qi stagnation, belongs to the category of “liver depression and qi stagnation” in traditional Chinese medicine, manifested as: depression, sighing at times, irritability and agitation, insomnia The symptoms are: depressed mood, sighing all the time, irritability and agitation, insomnia, dreaminess, chest and liver pain, chest tightness or abdominal fullness and pain, decreased appetite with abdominal pain and constipation, diarrhea, breast pain, irregular menstruation, dysmenorrhea, etc. Through the method of “dredging the liver, regulating qi, strengthening the spleen, and relieving depression” in Chinese medicine, we can achieve the effect of dredging the qi of the liver, relieving the depression of qi and restoring the function of the liver.