The causes of patients with enlarged lymph nodes in the ileocecal region are commonly seen in the following clinical situations I. Patients with acute suppurative appendicitis, as acute suppurative infection of the appendix can cause inflammatory enlargement of the ileocecal lymph nodes. Patients can have abdominal pain, abdominal distension, chills, high fever and other systemic inflammatory reactions. Surgery is needed to remove the appendix, clean the abdominal cavity and strengthen anti-infection treatment in order to gradually absorb and subside the enlarged lymph nodes in the ileocecal region and achieve better treatment results. If the tumor cells block the intestinal canal, the patient will have obvious abdominal pain, abdominal distension, nausea, vomiting, anal stoppage, defecation and other intestinal obstruction performance. Patients can be examined by colonoscopy to clarify the exact location of the tumor lesion. Surgery should be performed as soon as possible to remove the tumor in the ileocecal region and clear the local lymph nodes. After surgery, combined with chemotherapy and radiotherapy, most patients can often achieve better results.