Chronic poisoning is mostly caused by long-term or overdose of certain drugs, mostly seen in sedative drugs, antiepileptic drugs, digitalis-type cardiac drugs, and patients are advised to use the drugs correctly under the guidance of the doctor for treatment. 1. Sedative drugs: including eszopiclone tablets, alprazolam tablets, etc., perennial insomnia patients may be due to long-term high-dose abuse, chronic poisoning. After poisoning, patients may show dependence on drugs, uncoordinated body movement and mental symptoms. 2. Antiepileptic drugs: including carbamazepine tablets, sodium valproate tablets, etc., mainly used in the treatment of epileptic seizures, overdosage may cause the patient to develop chronic toxic reactions, such as nystagmus. 3. Digitalis-type cardiac drugs: such as digoxin tablets, mainly used for arrhythmia and chronic heart failure patients, long-term application may cause chronic poisoning, the patient may be manifested as arrhythmia, and nausea, vomiting and other gastrointestinal symptoms. The above types of drugs in the body to accumulate to a certain concentration, may produce organ damage, chronic toxic reactions. So once in the process of taking medication, there is obvious discomfort, patients should go to the hospital in time to consult, identify the cause.