Drugs are an important cause of liver damage. The mechanisms by which drugs cause liver disease vary from drug to drug, are very complex, and in most cases are not known. Some drugs have direct toxic effects and the liver damage caused by them is generally predictable, and the damage is dose-related and specific to certain drugs; other drugs cause liver damage only occasionally in sensitive individuals and are dose-independent and unpredictable in occurrence. There is a wide range of drugs that cause drug-related liver damage, and there are many Chinese and Western drugs that are hepatotoxic. The most common Western drugs are: 1, antibiotics, such as anti-tuberculosis drugs rifampin, isoniazid, etc.; macrolides, such as erythromycin, spiramycin, etc.; tetracyclines, etc. 2, antipyretic and analgesic drugs: aspirin, pautazone, etc. 3.Anti-psychotic drugs: chlorpromazine, fenadine. 4, antidepressants: amitriptyline. 5, anti-epileptic drugs: sodium valproate. 6, sedative drugs: phenobarbital, etc. 7.Anti-hyperthyroidism drugs: tabazol, methylphenidate, propylthioxypyrimethamine, etc. 8.Anti-tumor drugs: mitomycin, rejuvenomycin, cyclophosphamide, etc. 9.Glucose-lowering drugs: euglycemia, bethanechol, etc. 10.Cardiovascular drugs: Isoptin, Amprolium, etc. Chinese herbal medicines include Qing Dai, Neem, Shan Dou Root, Shan Ciguan, etc.