Peptic ulcers are mainly chronic ulcers that occur in the stomach and duodenum. Gastric ulcers and duodenal ulcers are not the same disease, and there are obvious differences in the etiology and pathogenesis of the two. However, they have a lot in common in terms of epidemiology and clinical manifestations, so they are collectively referred to as peptic ulcers. It is generally believed that peptic ulcers are caused by a multifactorial etiology, including attack by gastric acid and pepsin; infection by Helicobacter pylori; abnormal gastric motility; psychiatric and dietary factors, etc. However, in general, the balance between the defense mechanism of the gastric mucosa and the aggressive factors on the gastric mucosa is compromised. How to distinguish gastric ulcer from duodenal ulcer? 1. The typical symptoms of peptic ulcer are: dull pain, burning pain, distension and severe pain in the upper abdomen, with most of the painful areas located under the glabella in the upper abdomen. However, there are certain ways to distinguish the two. 2, duodenal ulcer: pain often appears between meals and at night, and the pain can be significantly better after eating. In contrast, the pain of gastric ulcer mostly appears about half an hour to one hour after a meal. 3, peptic ulcers are prone to complications such as peptic bleeding, perforation, pyloric obstruction and cancer, so it is especially important to get regular and correct treatment early. The purpose of treatment is to control symptoms, promote ulcer healing, prevent recurrence and avoid complications.