The relationship between physical activity and cancer has been less studied in the past, and it is only recently that the need for regular, moderate, or occasionally heavy physical activity has been recognized. Physical activity refers to any form of physical activity performed through skeletal muscles. People have been performing regular activities for survival since childhood, and in ancient times, people had to improve their lives and sustain themselves through physical labor, which included basic walking and toiling as the only way to achieve life and reproduction. But with urbanization and industrialization, the overall level of physical activity tended to decline, and machines did most of the work previously done by hand. Early factory and mechanical work often still required moderately intense labor, but as industrialization continued, household chores and work practices became increasingly mechanized and automated, with driving and transportation largely replacing walking and bicycling. Most urban dwellers may engage in some active recreational activities, but overall they remain inactive, and many are accustomed to spending much of their time on sedentary-based recreational activities such as watching television and playing on the computer. A sedentary lifestyle unknowingly brings us numerous health problems and is a major potential cause of death, disease and disability. The World Health Organization Behavioral Risk Factor Study shows that a sedentary lifestyle is one of the top ten causes of death and disability, increasing mortality from almost all diseases and increasing the risk of developing cardiovascular diseases such as hypertension, type II diabetes, obesity, colon cancer, endometrial cancer, breast cancer, fat metabolism disorders, osteoporosis, depression and anxiety. According to statistics, close to 2 million deaths worldwide each year are associated with a sedentary lifestyle. Since the early 1990s, a large number of articles have been published on the subject of physical activity and cancer risk. This evidence suggests that engaging in regular, consistent physical activity can prevent cancer in certain areas, for example, exercise has been shown to reduce the incidence of colon cancer and estrogen-related cancers (breast and endometrial cancer). It is certain that moving away from a sedentary lifestyle is effective in reducing the incidence of cancer. The easiest way to move away from a sedentary lifestyle is to get moving. The impact of physical activity on health depends on its mode, intensity, duration and frequency. Available evidence shows that: people who usually lack physical activity can improve their health and quality of life if they can regularly (e.g., more than 3 times a week) participate in moderate intensity physical activity; less intense physical activity also has a role in promoting health, but the benefits are relatively limited; moderate increases in physical activity (time, frequency, intensity) can yield greater health benefits; different forms of physical activity, time, intensity, frequency, and frequency of physical activity can have a positive impact on health. Different forms, time, intensity, frequency and total amount of physical activity have different health-promoting effects. Therefore, we need to achieve as much activity as possible in our daily life by various means. In general, when the human body exercises vigorously, the amount of oxygen digested by the body and the heart rate can reach the limit level, the oxygen consumption at this time is called the maximum oxygen consumption, the corresponding heart rate is the maximum heart rate, the maximum heart rate can also be calculated by 220 minus age, when the heart rate reaches 60% to 75% of the maximum heart rate, the level of physical activity is generally considered to have reached a medium intensity. 150 minutes of moderate intensity per week can improve cardiorespiratory fitness, lower blood pressure and blood sugar, improve blood lipids, regulate the endocrine system, increase bone density, and control unhealthy weight gain. According to current evidence, the total amount of physical activity that is beneficial to health is that physical activity should be of moderate intensity and above, and the frequency should be 3 to 5 days per week. In fact, in addition to regular weekly exercise, we can also use some of the free time at work, busy to move the body, as long as you can avoid the body in a static state, to avoid a long time a posture, all the small movements are beneficial. Like squatting, stretching, leg press and other simple movements can help eliminate fatigue and promote blood circulation. In fact, the main reason why people are not willing to exercise or participate in sports is ultimately the lack of ideological attention to the benefits and hazards of exercise or not to the body lack of sufficient knowledge, busy and no time is the most common excuse people use. The key to changing the sedentary lifestyle is to pay attention to the mind and perseverance, physical diseases are not developed in a day or two, and a healthy body is not dependent on a day or two of exercise can be obtained. From now on, let’s squeeze out a little time for exercise every day for our health, be persistent and let our body move, so that our body will be more energetic and cancer will be farther away from us.