Most depression in secondary school students can be cured with systematic and standardized treatment. Current research shows that the cure rate of depression is about 50%-90% after systematic and standardized treatment with antidepressants and psychotherapy. The cure rate of different drugs is different. The commonly used antidepressants are selective 5-hydroxytryptamine reuptake inhibitors, commonly used are sertraline, fluoxetine, paroxetine, citalopram, fluvoxamine and other 5 golden flowers, as well as dual-channel drugs such as duloxetine, venlafaxine and so on. There are also some other commonly used herbal medicines, such as de-livering and depression capsule, tranquilizer and brain tonic, and depression pills, etc. These medicines are very good and their efficacy is very certain, and most of them can be cured after an active full amount and full course of treatment. At the same time, you can also choose a suitable psychological treatment method, if the depression of secondary school students comes from their own relationship with their families, or with their parents, you can choose family psychotherapy, such as about their parents together to the counselor to learn to understand each other, learn to understand the attitude of others and the views of others, encourage and support each other, only in this way can slowly get better Only in this way can we slowly improve.