Uric acid is the end product of purine metabolism and is mainly produced by the enzymatic breakdown of nucleic acids and other purine analogues from cellular metabolism as well as purines from food. The saturation and concentration of uric acid in the body at 37°C is about 420 μmol/L (7 mg/dl), above which hyperuricemia is considered. Hyperuricemia prefers men. Most patients with primary hyperuricemia start without clinical symptoms, often with manifestations of metabolic syndrome, and prolonged hyperuricemia may lead to gout, hence the symptoms of gout. Therefore, the main symptoms of hyperuricemia are: 1, asymptomatic phase: only fluctuating or persistent hyperuricemia, the time from the increase of blood uric acid to the appearance of symptoms can vary from several years to decades, some can be lifelong without symptoms, but the prevalence of gout increases with age. 2, gouty arthritis: often first in the first metatarsophalangeal joint, or ankle, knee joints, the onset of the disease is rapid, the first attack often involves a single joint, can be spontaneous remission, repeated attacks will gradually increase the number of joints involved. Gout stones: In patients with untreated first symptoms, gout stones may appear in about 70% of patients after many years, often in the first metatarsophalangeal joint, auricle, forearm extension, finger joints, elbow joints and other parts. 4, renal lesions: mainly in gouty nephropathy and uric acid kidney stones. 5. Eye lesions: those with longer disease duration may develop gout stones, recurrent conjunctivitis, keratitis and sclerenitis. Therefore, in men with high uric acid, some of them have no clinical symptoms, and some of them will have the above clinical symptoms, and the symptoms need to be combined with the patient’s medical history and related examinations to further confirm the diagnosis.