At present, chemotherapy is one of the ways to treat advanced liver cancer. The clinical evaluation of the effect of chemotherapy on advanced liver cancer is not very high, mainly because patients with advanced liver cancer are often combined with cirrhosis and have different degrees of liver function damage, and the toxic side effects of chemotherapy can further damage liver function and aggravate the patient’s condition. Surgery is also a common treatment method for advanced liver cancer. If the metastatic site is single, the tumor is small and the patient is physically able to withstand surgery, surgical resection can be considered. However, generally speaking, surgical resection is not advocated for advanced liver cancer treatment, because patients with advanced liver cancer are not suitable for surgical treatment due to their weak constitution or the development of metastasis. There is another way to treat advanced liver cancer, which is to adopt “III generation of light-transmitting regenerative technology”. The third-generation light-transmitting regenerative technology firstly uses the electromagnetic effect generated by high-definition positioning medium-frequency laser from crystal laser generator to block the virus replication chain, destroy virus molecules, toxin molecules and degrade fiber molecules. It stimulates hepatocytes to secrete cytokines to identify low-activity cells, heterotypic cells, and infected cells to remove viruses and toxins. Cut off the energy supply of abnormal cells and switch to provide energy for normal liver cells. Using biofilm permeation extraction technology and genetic recombination molecular synthesis technology to permeate the drug, open ion channels, make the drug more efficient and reach the patient’s foci, unblock the five major pathways of the liver, improve the micro-ecological environment of the liver to facilitate detoxification, regenerate liver cells, wake up damaged liver cell tissues and poorly active abnormal cells, soften cirrhotic nodules. The liver function is reshaped and healthy liver cells with initial vitality are transformed, and the source of liver treatment replaces single treatment to achieve clinical recovery.