Gliomas are one of the most challenging categories of neurosurgery. Due to their complex growth characteristics and the wide variety of gliomas, survival is low in most cases. Therefore, treatment becomes a major challenge for glioma. However, overtreatment of glioma is often found in clinical practice. What is overtreatment and what is a reasonable treatment for glioma? How to prevent overtreatment of glioma: The so-called “overtreatment” refers to the treatment measures and intensity given by the doctor to the patient exceeds the patient’s treatment needs, which not only causes unnecessary pain and damage to the patient’s body, but also costs a lot of money and makes the patient worse. As patients and their families fear recurrence after diagnosis, there are also doctors who worry about patients’ recurrence and treat them unnecessarily and repeatedly. Although it is recommended to start radiotherapy as soon as possible about 2-4 weeks after surgery, X-knife or gamma knife or proton knife are not recommended as post-surgical treatment for malignant glioma to avoid over-treatment after surgery. Radiation therapy does not benefit from increasing the dose of tumor irradiation within a certain dose range. Increased doses of brachytherapy and changes in segmentation modality have no effect on survival. After six months to one year or even two years of Gamma Knife or X Knife treatment, radiation necrosis in the treated area often occurs, cerebral edema around the radiation area, and patients have increased headache and vomiting, and even epilepsy, drowsiness, hemiplegia and aphasia inability to walk. The radiation necrosis is often aggravated gradually with the prolongation of time, and the lesions of radiation necrosis are gradually enlarged, which is very difficult to distinguish from tumor recurrence. Especially after general radiotherapy or conformal intensity modulated radiotherapy, and then X-knife or gamma knife or proton knife treatment, most of them will have radiation necrosis of brain tissue. This kind of radiation damage is difficult to treat, basically there is no effective treatment, and it may cause disability and death of patients in serious cases. It causes great suffering to patients and their families and makes further treatment very difficult for doctors. Therefore, once patients find themselves suffering from nausea glioma, they must be treated scientifically and look at the condition rationally, not to imply that the pursuit of treatment leads to over-treatment, which often results in more losses than gains.