Glutamyl transpeptidase is an enzyme that exists in every organ in the human body. Serum transpeptidase mainly comes from liver cells, when suffering from liver diseases or liver cell damage caused by other factors, transpeptidase is released into the blood from broken liver cells, resulting in higher test results. The normal reference value of glutamyl transpeptidase is between 3-50U/L. 187U/L belongs to serious high, and the cause of the disease should be clarified in time and treatment should be given according to the cause. Its treatment is as follows: 1, long-term alcohol consumption leads to alcoholic liver injury, alcoholic hepatitis, at this time you need to completely quit drinking, eat reasonably, and avoid contact with alcohol or alcoholic beverages; 2, long-term use of drugs leads to medication liver injury, don’t continue to take the drugs that are damaging to the liver, and regularly review and observe the changes in the enzyme of glutamyltranspeptidase; 3, there is a fatty liver, and the pressure of the fat leads to the injury of the bile ducts, which will show an increase in this indicator. This indicator is elevated. If there is fatty liver, we must have low cholesterol diet and strengthen exercise, that is, keep your mouth shut and keep your legs open; 4. If you consider that it is caused by jaundice hepatitis, which is related to viral infection, the patient will have the symptoms of anorexia, nausea, etc., it is recommended to do liver biopsy, and you can take ursodeoxycholic acid to treat it; 5. If it is caused by hepatocellular carcinoma, it is recommended to do hepatic puncture, and it can be interventional therapy or hepatic resection treatment.