In recent days, I have seen two consecutive cases of post-stroke depression, and I think it is important to let people know about it. Some patients cry a lot, especially when they are visited by relatives and friends. Some patients are reluctant to see relatives and friends, silent, fatigued and weak, which seriously affects the rehabilitation effect and prognosis. They may even have suicidal thoughts. At this time, great psychological comfort and collective family counseling are needed. Each patient needs a period of time to adapt, so family members and doctors must have great patience to ensure that the patient passes through this stage peacefully in order to obtain the maximum recovery effect. Oral antidepressants are also used to relieve symptoms.