Patients with food poisoning fever for two days should have a light diet, bed rest, and increase the amount of water intake appropriately; antibiotic drugs (e.g., cefixime, cefradine, etc.) can be used under doctor’s supervision; physical cooling (e.g., using fever-reducing patches, warm-water baths, etc.) can be used to reduce the fever as early as possible. Food poisoning is an acute toxic illness caused by food contaminated with bacteria or bacterial toxins, or food containing toxins. There will mainly be some symptoms such as fever, abdominal pain, diarrhea, nausea and vomiting. If the symptoms are not serious and the body temperature does not exceed 38.5℃, bed rest should be provided and the early diet should be an easy-to-digest liquid or semi-liquid diet. Salmonella food poisoning should be isolated at bedside. Drink plenty of fluids and monitor the body temperature. Physical cooling (e.g. antipyretic patches, warm water baths for limbs, etc.) can be used. If the temperature exceeds 38.5 ℃, should promptly seek medical attention, under the guidance of the doctor, can be according to different pathogenic bacteria selection of antibacterial drugs. Such as Salmonella, Vibrio parahaemolyticus can choose quinolone antibiotics.