There are many causes of numbness in the palms of the hands, but they are usually not a sign of any disease. 1. carpal tunnel syndrome: wrist pressure, long-term overuse of the wrist can lead to increased pressure in the carpal tunnel, often manifested in the palm of the hand numbness, tingling sensation. 2. cervical spondylosis: mostly caused by long-term poor posture and other reasons, due to the cervical vertebrae or intervertebral disc compression of the nerves, resulting in numbness in the palm of the hand. 3. Diabetes mellitus: prolonged hyperglycemic state leads to peripheral nerve damage, which can appear in the hands and cause numbness and tingling. 4. Thromboembolic vasculitis: early symptoms can show a series of manifestations such as coldness, numbness and nutritional disorders in the distal limbs. 5. Peripheral neuritis: if the patient has poor digestion and absorption function for a long time, it will cause vitamin B1 deficiency, which will lead to peripheral neuritis, and also cause numbness of the palm. The symptoms of numbness in the palm of the hand, it is recommended to go to the hospital in time, and actively cooperate with the doctor for treatment.