Nodular acne is a type of severe acne, characterized clinically by polymorphic lesions such as pimples, papules, pustules, and nodules that are commonly found on the face. When nodules or cysts become volatile or pus-filled, they are usually discharged clinically through surgery or medication.1. Surgery: The surgical procedure generally begins with disinfection of the local skin surface, followed by a linear incision on the surface of the nodule or cyst with a scalpel, and the secretions are discharged after the health care worker wears gloves and is fully disinfected. After the discharge of the secretion, local flushing is carried out, and then gentamicin and tretinoin are injected to prevent infection and inflammation subsidence. 2. If necessary, oral antibiotics can be used for antibacterial treatment. In addition, nodular acne can also be treated by red and blue light irradiation and fractional laser. In the process of treating nodular acne, it is important to pay attention to skin cleansing and try to choose a mild oil-controlling and hydrating cleanser.