Cirrhosis is a very common clinical chronic liver disease, the onset of which is mainly related to long-term chronic hepatitis, alcoholism, parasitic diseases of the liver, autoimmune diseases and so on. I. Symptoms: 1. Abnormal liver function indexes of different severity. Naturally, there will be some such as fatigue, loss of appetite, postprandial bloating, epigastric pain and diarrhea, etc. The nutritional status of the patients is poor, and some of the patients have a grayish face, and the spider nevus of the liver palm can also be seen. Imaging examination suggests that the liver is shrunken or morphologically altered and hard, and the spleen is enlarged and hard. 2. Secondary manifestations of portal hypertension: esophageal varices, splenomegaly and ascites. The incidence of hepatocellular carcinoma on the basis of long-term cirrhosis is also increased. And portal hypertension triggers anemia, bleeding tendency, even rupture and bleeding of esophagogastric fundus vein, and the mortality rate of the latter will be higher. Advanced cirrhosis is mainly manifested in hepatic coma, intractable ascites, hepatorenal syndrome, jaundice and so on. Surgical indications Cirrhosis treatment should follow the principles of specialization, individualization and combination of internal and external surgery. 1. Early and middle stage of cirrhosis should adhere to dietary regulation and moderate rest as well as drug therapy, and liver protection drugs and anti-virus replication drugs should be used for whether hepatitis virus replication is combined or not, respectively. Appropriate oral vitamins, amino acids and energy synthesizing drugs, avoid large exercise, pay attention to the combination of work and rest. The diet should be rich in nutrients and easy to digest and absorb, with high calorie, high protein and vitamin-rich food. Reduce high fat content, high salt food. 2, secondary portal hypertension is mainly treated by surgery. For severe esophagogastric fundic varices, severe splenomegaly or severe hypersplenism, peripancreatic vascular dissection and splenectomy are adopted respectively. The benefits of surgery are: A Preventing and treating upper gastrointestinal hemorrhage caused by cirrhosis. B Correcting anemia due to hypersplenism. C Improvement of hepatic perfusion, reduction of portal pressure, improvement of liver function, and significant improvement of digestive function and quality of life. Any kind of liver cirrhosis surgery must be fully evaluated by specialized doctors before surgery, such as jaundice, large amount of ascites or severe hypoproteinemia are not suitable for surgery, surgery will lead to liver failure or even death and other serious consequences. 3. advanced cirrhosis is treated with comprehensive and conservative treatment. patients with end-stage cirrhosis under 60 years old can be considered for liver transplantation.