How to treat organophosphate poisoning

The treatment of organophosphate poisoning is mainly based on drug therapy, assisted by gastric lavage therapy and blood perfusion therapy. 1. Drug treatment: commonly used drugs include diarrhea-inducing drugs, antidotes, anticholinergic drugs, sedative drugs, rehydration and neurotrophic drugs. (1) Diarrheal drugs: such as magnesium sulfate, mannitol, etc., used to clear the intestinal tract of poison, usually after gastric lavage. (2) Antidotes: e.g., chlorophosphamide, iodophosphamide, etc., are used to counteract the muscle tremor symptoms that follow poisoning. (3) Anticholinergic drugs: such as atropine, etc., mainly used to relieve M-like symptoms and N-like symptoms caused by organophosphorus poisoning. (4) Sedative drugs: e.g. diazepam, midazolam, etc., used for sedative treatment. (5) Rehydration fluids: such as saline. Glucose injection and potassium chloride, etc., used to correct water electrolyte and acid-base balance disorders. 2. Gastric lavage treatment: use warm water, sodium bicarbonate, etc. to wash the stomach to promote the discharge of toxic substances. 3. Blood perfusion treatment: remove the toxic substances of internal and external origin with the help of extracorporeal circulation and purify the blood. If organophosphate poisoning occurs, it is recommended to consult a doctor for treatment in time and take medicines according to the doctor’s instructions, so as not to lead to a more serious condition.