【Case】 Soon after the new school year started, the cheerful, lively and generous Dandan became moody and unpredictable, upset at home, crying every 3-4 days, and her family could not persuade her, sometimes making excuses not to go to school. At first, the parents attributed this change in their 12-year-old daughter’s temperament to adolescent rebelliousness, thinking that this change in their daughter, who had always been strong, was just an inevitable part of growing up and that she would soon get better. But it turned out that everything was not as simple as the parents thought. Dandan was sad all day long, tearful at every turn, uninterested in anything, and gradually had poor sleep and loss of appetite, unable to manage interpersonal relationships with her classmates, unmotivated in class during the day, listening to lectures like “heavenly books”, losing confidence in herself and her future. He often blames himself for his “uselessness, he can’t do anything well”, and from time to time he says things like “there’s no point in living”. He once quietly cut his wrist with a knife and wanted to die, but he felt sorry for his parents. Seeing that the child’s mood was deteriorating, her anxious parents rushed to bring her to the psychological clinic for help. After my detailed examination, and based on Dan Dan’s clinical presentation and psychological tests, she was suffering from depression. [Analysis] In the eyes of many people, children and adolescents are in the beautiful flowering season of innocence and carefreeness, so it is difficult to associate children with depression as a disease. In fact, depression has become a common mental problem among children and adolescents. Studies have shown that about 20% of children in China are currently depressed, and 4% of them are clinically depressed, i.e., major depression that requires clinical treatment. Depression is known as the “mind cold” in the West, and it is a common disease like cold and flu, with an extremely common incidence. However, in the minds of many people, depression is not a disease at all, and is only considered to be a bad mood, while in fact, depression is a serious health hazard as diabetes, coronary heart disease, hypertension, peptic ulcer, etc. According to relevant information, in the twenty-first century, depression has become the second killer of human health among global diseases. In China, depression accounts for 50%-70% of suicide and attempted suicide, 15% of depressed patients eventually die by suicide, and among children and adolescents, suicide is still the second leading cause of death, second only to accidents. The current generation of only children has long been burdened with too much pressure beyond their age, academic performance, interpersonal conflicts, high parental demands, the pressure of competition …… data show that the prevalence of preschool children is about 0.3%, elementary school children about 2%, adolescents about 5% to 10%, the incidence of depression increases with age. The incidence of depression increases with age. In China, many people, even elementary school students, know the symptoms of the physical cold, but very few people know the symptoms of the “spiritual cold”. Children with depression are often confused about their moods and have depression as a core symptom. They are unable to accurately describe how they really feel, so they experience low mood, decreased interest, may complain about their physical discomfort, exaggerate their fears, feel bored, lack energy, and even talk about death. Typical depression has a rhythmic character, showing a changing pattern of heavy days and light nights. The basic clinical features of depression in children and adolescents are: ① Affective disorders: manifested by low mood, unhappiness, sadness, crying, low self-assessment, unwillingness to go to school, loss of interest in daily activities, not wanting to do anything, self-loathing, feelings of uselessness, wanting to die or attempting suicide. They also show sensitivity, irritability, temper tantrums, disobedience, restlessness, boredom, isolation, anger, and running away from home for no reason. (2) Psychomotor retardation: manifested as slow movement, reduced activity, and behavioral withdrawal. In severe cases, the patient may be in a state of wood stiffness, not talking and not moving. ③Thinking and speech disorders: slow thinking, whispering, reduced speech, slow speech, self-blame and low self-esteem. Older children may have delusions of guilt. ④Somatic symptoms: often complain of various physical discomfort, such as headache, dizziness, fatigue, chest tightness, shortness of breath, loss of appetite, sleep disorders, etc. ⑤ Behavioral disorders: Children and adolescents with depression may have behavioral disorders as prominent symptoms, such as disobedience, confrontation, impulsivity, excessive activity, aggressive behavior or other disciplinary misbehavior. Child and adolescent depression will not only seriously hinder the formation and development of a child’s healthy personality, temperament, perception and way of thinking, but will also have an impact on the child as an adult. Therefore, when parents find that their children are irritable, irritable, have mood swings for no reason, are always listless, can’t take interest in anything, don’t even bother to do what they usually like the most, also have panic attacks, chest tightness, stomach pain, more sleepy, can’t eat, feel very tired all day long, their performance at school becomes worse and worse, complain that life is too tired or too boring, feel that there is no point in living …… these may be endodynamic deficits, is the core symptoms of depression, if the duration of more than two weeks, and because the existence of symptoms has affected a person’s normal life and learning, it is easy to lead to suicide, should not be taken lightly, should be alert to depression, must promptly take the child to the psychiatric department or psychology to consult In order to early detection, early diagnosis and intervention treatment, in order to effectively help children get rid of the shadow of “mind flu”, reduce the risk of suicide and reduce functional impairment, and promote healthy growth.