Radical treatments for liver cancer include, surgical resection of liver cancer, liver cancer ablation and liver transplantation. Regardless of the treatment methods used, recurrence is possible after surgery. Therefore, it is clinically important to adopt appropriate methods to reduce the recurrence of liver cancer as much as possible. 1.Anti-viral treatment. Most of the occurrence of liver cancer in China is related to hepatitis B virus, then the recurrence of liver cancer is also closely related to hepatitis B virus, so anti-hepatitis B virus treatment is indispensable in reducing the recurrence of liver cancer. 2.Regulate immune function. The occurrence of tumor is often the result of the decrease of immune function of the body, and the same reason exists for the occurrence of liver cancer. Therefore, it is also beneficial for post-operative liver cancer patients to have immunomodulatory treatment. Besides, the destruction of liver cells by hepatitis B virus is also an immune response, so it is also helpful to carry out immunomodulatory therapy for the control of hepatitis B virus. 3. Targeted therapy. Doxorubicin (Sorafenib) is a targeted therapy drug targeting hepatocellular carcinoma cells and hepatocellular carcinoma blood vessels, which can theoretically reduce the recurrence of hepatocellular carcinoma.