Adenocarcinoma of the liver is a rare type of liver cancer, which includes other more common types, such as hepatocellular carcinoma, hepatobiliary cell carcinoma, etc. Adenocarcinoma of the liver is more malignant and less sensitive to chemotherapy and radiotherapy. The main treatment methods for adenocarcinoma of liver are surgery, interventional therapy, microwave ablation therapy, chemotherapy, radiotherapy, immunotherapy, targeted drug therapy, biological therapy, combined Chinese and Western medicine therapy, etc. Most patients with early to mid-stage liver cancer can be cured or have their life span prolonged through surgical treatment. For patients with advanced liver cancer, as long as the growth, development and spread of tumor can be controlled, patients can live with tumor and have their life span prolonged.