There is currently no cure for scleroderma, or systemic sclerosis, and early treatment is aimed at stopping new skin and organ involvement, while late treatment is aimed at improving existing symptoms. Systemic sclerosis is an autoimmune connective tissue disease characterized by limited or diffuse skin thickening and fibrosis with multiple organ involvement, and there is no cure. Treatment includes glucocorticoids (e.g., prednisone), immunosuppressants (methotrexate, cyclophosphamide), calcium antagonists (nifedipine), and diuretics (furosemide). Treatment options vary depending on the severity of the disease and the organs involved. After diagnosis of systemic sclerosis, it is recommended to go to the hospital for standardized treatment as soon as possible to avoid delaying the disease, and the drugs should be used according to the prescription, do not use on your own.