Thalassemia causes weak pulse mostly in infancy, manifesting as anemia, weakness, and intra-abdominal masses. Most thalassemias are caused by anemia, weakness, abdominal masses, developmental delay, etc. Heavy cases are associated with poor growth and development and often die before adulthood. As a genetic disease, thalassemia is basically incurable. The best way to prevent and treat thalassemia is to prevent children with thalassemia major from being born. If you can clearly understand your genetic background before marriage, and do prenatal screening and diagnosis of thalassemia, you can effectively minimize the chance of the next generation having thalassemia major. 1. Pre-marital examination: The appearance of thalassemia carriers is no different from normal people, so it is important to carry out population screening and genetic counseling, and to provide good pre-marital guidance to avoid marriages between carriers of the gene for thalassemia to prevent this disease. 2. Prenatal examination: If both husband and wife are carriers, the fetus should be taken for physical examination after the 12th week of pregnancy, and if it is determined that the fetus is heavy with thalassemia, the pregnancy can be interrupted to avoid the occurrence of fetal edema syndrome and the birth of patients with heavy β thalassemia.