Cured discharge of patients with neoconiosis should be consistent with two consecutive negative nucleic acid tests with a sampling interval of at least 24 hours. However, the degree of difficulty in specimen collection and the influence of many factors in the testing process can have an impact on the accuracy of the nucleic acid test and may lead to false negative results. Individual patients have been found to have a re-positive nucleic acid test after discharge from the hospital. Therefore, it is recommended that patients discharged from the hospital for recovery continue to be isolated for two weeks to ensure safety. During the isolation period, it is important to cooperate with the healthcare provider for 14 days of self-health status monitoring, wear a mask, practice hand hygiene, and avoid going outside activities. In addition, after discharge, patients may be at risk of infection with other pathogens due to the low immune function of the recovering organism. Precautions should also be taken.