In recent days, the temperature difference between day and night is large, and the immune function of patients with chronic hepatitis B is easily affected by cold, while immune dysfunction in patients with liver disease is a basic cause of liver disease recurrence. Special reminder, the weather changes, chronic hepatitis B and other liver disease patients should do a good job of their own health management, regular review. According to some data, the peak of liver disease recurrence in autumn and winter lasts longer than that in spring, and 47% of chronic hepatitis B patients have their existing liver disease aggravated by various infections, such as upper respiratory tract infections caused by cold and flu, abdominal infections, overlapping hepatitis infections, intestinal infections, etc. Therefore, Professor Hou reminded chronic hepatitis B patients to pay attention to their health management in daily life in autumn and winter, in addition to receiving regular treatment. Do the following five points: First, pay attention to the living, life should be regular. Pay attention to the cold to keep warm, avoid catching cold, keep enough rest and sleep, do not stay up late. The liver has the function of storing blood and regulating the amount of circulating blood, after lying down to sleep, the blood flow of the liver can increase by 1000-2000 ml, so patients with liver disease need to ensure 8 hours of sleep every day, so that the liver can get sufficient rest and recuperation. Second, good emotional management, maintain a good state of mind. The development of hepatitis largely depends on the immune status of the individual, and the immune status is closely related to personal emotions. The Chinese have always said “sad autumn”, therefore, patients should pay attention to maintain an optimistic mood, change the sad autumn to happy autumn, avoid anger, depression, etc., to maintain an open mind, so as not to lead to aggravation of the disease. Third, a reasonable diet, low fat, low sugar, high nutrition, high vitamin diet, pay attention to a reasonable mix of three meals a day, soft and hard suitable, light diet, can to a certain extent promote the recovery and regeneration of liver cells. Fourth, reasonable exercise, the principle of not fatigue, reasonable exercise to enhance the body’s immunity. Fifth, quit smoking, drinking alcohol and other bad habits. Such as long-term large amounts of alcohol intake can cause several different lesions of the liver, the lighter only fatty degeneration, the heavier the formation of alcoholic hepatitis and liver fibrosis, and then the development leads to irreversible cirrhosis of the liver. Early detection and treatment of chronic hepatitis B patients are especially reminded that most hepatitis B relapses are insidious and not easily detected, so attention should be paid to follow-up liver function tests in the fall and winter when the climate changes significantly. The purpose of liver function tests is to detect the presence of liver disease, the degree of liver damage and to identify the causes of liver disease, determine the prognosis and identify the causes of jaundice, etc. Chronic hepatitis B patients who have been asymptomatic for a long time and hepatitis B virus carriers should pay particular attention to liver function tests, and should go to the hospital in a timely manner when there are obvious symptoms such as decreased appetite, fatigue, dry mouth and bitterness, so as not to delay treatment and aggravate the disease.