Whether high-risk HPV18 positive can be cured or not is related to the duration of infection and whether it causes cervical lesions, and needs to be judged in the context of the patient’s specific situation. Usually, if the patient has been infected with high-risk HPV18 positive for a relatively short period of time and has not caused cervical lesions, it may heal on its own or medication can be applied to achieve a cure; if the infection is longer and has caused cervical lesions, it needs to be judged whether it can be cured according to the type of lesions. High-risk HPV18 positive, if the patient has been infected for a relatively short period of time, has not caused cervical lesions, and has a high body immunity and a normal local immune environment of the cervix, usually more than 90% of people naturally turn negative within two years, that is, self-healing, or interferon plugs can be applied to promote the turn to cure, the chance of cervical lesions will be reduced after turning negative, but regular TCT and HPV examinations are needed; high-risk HPV18 positive, if the viral infection lasts longer and the viral load is higher, the local environment of the cervix is poorer, and cervical biopsy is done to find cervical intraepithelial neoplasia, precancerous lesions or even cervical cancer, whether this case of HPV18 positive can be cured needs to be judged with the type of lesion. Usually, cervical intraepithelial neoplasia and precancerous lesions have a higher chance of being cured, while cervical cancer has a higher clinical cure rate when detected early, but a lower cure rate when detected later. In daily life, we should also pay attention to less spicy and oily stimulating food and pay attention to menstrual hygiene.